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Computer-Aided Estimation of Biological Activity Profiles of Drug-Like Compounds Taking into Account Their Metabolism in Human Body

Most pharmaceutical substances interact with several or even many molecular targets in the organism, determining the complex profiles of their biological activity. Moreover, due to biotransformation in the human body, they form one or several metabolites with different biological activity profiles....

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Detalles Bibliográficos
Autores principales:	Filimonov, Dmitry A., Rudik, Anastassia V., Dmitriev, Alexander V., Poroikov, Vladimir V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593915/ https://www.ncbi.nlm.nih.gov/pubmed/33050610 http://dx.doi.org/10.3390/ijms21207492

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