Three-Dimensional Structures of Carbohydrates and Where to Find Them

Analysis and systematization of accumulated data on carbohydrate structural diversity is a subject of great interest for structural glycobiology. Despite being a challenging task, development of computational methods for efficient treatment and management of spatial (3D) structural features of carbo...

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Detalles Bibliográficos
Autores principales: Scherbinina, Sofya I., Toukach, Philip V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593929/
https://www.ncbi.nlm.nih.gov/pubmed/33081008
http://dx.doi.org/10.3390/ijms21207702
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author Scherbinina, Sofya I.
Toukach, Philip V.
author_facet Scherbinina, Sofya I.
Toukach, Philip V.
author_sort Scherbinina, Sofya I.
collection PubMed
description Analysis and systematization of accumulated data on carbohydrate structural diversity is a subject of great interest for structural glycobiology. Despite being a challenging task, development of computational methods for efficient treatment and management of spatial (3D) structural features of carbohydrates breaks new ground in modern glycoscience. This review is dedicated to approaches of chemo- and glyco-informatics towards 3D structural data generation, deposition and processing in regard to carbohydrates and their derivatives. Databases, molecular modeling and experimental data validation services, and structure visualization facilities developed for last five years are reviewed.
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spelling pubmed-75939292020-10-30 Three-Dimensional Structures of Carbohydrates and Where to Find Them Scherbinina, Sofya I. Toukach, Philip V. Int J Mol Sci Review Analysis and systematization of accumulated data on carbohydrate structural diversity is a subject of great interest for structural glycobiology. Despite being a challenging task, development of computational methods for efficient treatment and management of spatial (3D) structural features of carbohydrates breaks new ground in modern glycoscience. This review is dedicated to approaches of chemo- and glyco-informatics towards 3D structural data generation, deposition and processing in regard to carbohydrates and their derivatives. Databases, molecular modeling and experimental data validation services, and structure visualization facilities developed for last five years are reviewed. MDPI 2020-10-18 /pmc/articles/PMC7593929/ /pubmed/33081008 http://dx.doi.org/10.3390/ijms21207702 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Scherbinina, Sofya I.
Toukach, Philip V.
Three-Dimensional Structures of Carbohydrates and Where to Find Them
title Three-Dimensional Structures of Carbohydrates and Where to Find Them
title_full Three-Dimensional Structures of Carbohydrates and Where to Find Them
title_fullStr Three-Dimensional Structures of Carbohydrates and Where to Find Them
title_full_unstemmed Three-Dimensional Structures of Carbohydrates and Where to Find Them
title_short Three-Dimensional Structures of Carbohydrates and Where to Find Them
title_sort three-dimensional structures of carbohydrates and where to find them
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593929/
https://www.ncbi.nlm.nih.gov/pubmed/33081008
http://dx.doi.org/10.3390/ijms21207702
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