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Mechanism of the Affinity-Enhancing Effect of Isatin on Human Ferrochelatase and Adrenodoxin Reductase Complex Formation: Implication for Protein Interactome Regulation

Isatin (indole-2, 3-dione) is a non-peptide endogenous bioregulator exhibiting a wide spectrum of biological activity, realized in the cell via interactions with numerous isatin-binding proteins, their complexes, and (sub) interactomes. There is increasing evidence that isatin may be involved in the...

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Detalles Bibliográficos
Autores principales: Ershov, Pavel V., Veselovsky, Alexander V., Mezentsev, Yuri V., Yablokov, Evgeniy O., Kaluzhskiy, Leonid A., Tumilovich, Anastasiya M., Kavaleuski, Anton A., Gilep, Andrei A., Moskovkina, Taisiya V., Medvedev, Alexei E., Ivanov, Alexis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593955/
https://www.ncbi.nlm.nih.gov/pubmed/33066693
http://dx.doi.org/10.3390/ijms21207605