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Population Analysis of Staphylococcus aureus Reveals a Cryptic, Highly Prevalent Superantigen SElW That Contributes to the Pathogenesis of Bacteremia
Staphylococcal superantigens (SAgs) are a family of secreted toxins that stimulate T cell activation and are associated with an array of diseases in humans and livestock. Most SAgs produced by Staphylococcus aureus are encoded by mobile genetic elements, such as pathogenicity islands, bacteriophages...
Autores principales: | Vrieling, Manouk, Tuffs, Stephen W., Yebra, Gonzalo, van Smoorenburg, Marleen Y., Alves, Joana, Pickering, Amy C., Park, Joo Youn, Park, Nogi, Heinrichs, David E., Benedictus, Lindert, Connelley, Timothy, Seo, Keun Seok, McCormick, John K., Fitzgerald, J. Ross |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593966/ https://www.ncbi.nlm.nih.gov/pubmed/33109757 http://dx.doi.org/10.1128/mBio.02082-20 |
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