Aberrant Intracellular pH Regulation Limiting Glyceraldehyde-3-Phosphate Dehydrogenase Activity in the Glucose-Sensitive Yeast tps1Δ Mutant

Whereas the yeast Saccharomyces cerevisiae shows great preference for glucose as a carbon source, a deletion mutant in trehalose-6-phosphate synthase, tps1Δ, is highly sensitive to even a few millimolar glucose, which triggers apoptosis and cell death. Glucose addition to tps1Δ cells causes deregula...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Leemputte, Frederik, Vanthienen, Ward, Wijnants, Stefanie, Van Zeebroeck, Griet, Thevelein, Johan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593968/
https://www.ncbi.nlm.nih.gov/pubmed/33109759
http://dx.doi.org/10.1128/mBio.02199-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593968/
https://www.ncbi.nlm.nih.gov/pubmed/33109759
http://dx.doi.org/10.1128/mBio.02199-20

Ejemplares similares