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Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Experimental evidence highlights nuclear factor (erythroid-derived 2)-like 2 (Nrf2) as a molecular target in Alzheimer’s disease (AD). The well-known effect of electrophilic cysteine-reactive skin allergens on Nrf2-activation led to the hypothesis that these compounds could have a therapeutic role i...

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Detalles Bibliográficos
Autores principales: Silva, Ana, Pereira, Marta, Carrascal, Mylène A., Brites, Gonçalo, Neves, Bruno, Moreira, Patrícia, Resende, Rosa, Silva, Maria Manuel, Santos, Armanda E., Pereira, Cláudia, Cruz, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594024/
https://www.ncbi.nlm.nih.gov/pubmed/33096789
http://dx.doi.org/10.3390/ijms21207791

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