Identification of Novel Thiazolo[5,4-b]Pyridine Derivatives as Potent Phosphoinositide 3-Kinase Inhibitors

A series of novel 2-pyridyl, 4-morpholinyl substituted thiazolo[5,4-b]pyridine analogues have been designed and synthesized in this paper. These thiazolo[5,4-b]pyridines were efficiently prepared in seven steps from commercially available substances in moderate to good yields. All of these N-heteroc...

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Detalles Bibliográficos
Autores principales: Xia, Liang, Zhang, Yan, Zhang, Jingbo, Lin, Songwen, Zhang, Kehui, Tian, Hua, Dong, Yi, Xu, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594053/
https://www.ncbi.nlm.nih.gov/pubmed/33053730
http://dx.doi.org/10.3390/molecules25204630

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