Cargando…
C4-Alkylamination of C4-Halo-1H-1-tritylpyrazoles Using Pd(dba)(2) or CuI
Alkylamino coupling reactions at the C4 positions of 4-halo-1H-1-tritylpyrazoles were investigated using palladium or copper catalysts. The Pd(dba)(2) catalyzed C-N coupling reaction of aryl- or alkylamines, lacking a β-hydrogen atom, proceeded smoothly using (t)BuDavePhos as a ligand. As a substrat...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594063/ https://www.ncbi.nlm.nih.gov/pubmed/33053697 http://dx.doi.org/10.3390/molecules25204634 |