Stereoselective Synthesis of Spirooxindole Derivatives Using One-Pot Multicomponent Cycloaddition Reaction and Evaluation of Their Antiproliferative Efficacy

[Image: see text] A highly stereoselective, one-pot, multicomponent method has been developed to synthesize pyrrolizidine- and N-methyl pyrrolidine-substituted spirooxindole derivatives. The [3 + 2] cycloaddition reaction involves the reaction between the dipole azomethine ylides, generated in situ...

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Detalles Bibliográficos
Autores principales: Ghosh, Rajat, Vitor, Jorge B., Mendes, Eduarda, Paulo, Alexandra, Acharya, Pratap Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594148/
https://www.ncbi.nlm.nih.gov/pubmed/33134696
http://dx.doi.org/10.1021/acsomega.0c03675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594148/
https://www.ncbi.nlm.nih.gov/pubmed/33134696
http://dx.doi.org/10.1021/acsomega.0c03675

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