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Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer
INTRODUCTION: Patients with diabetes have increased risk of periodontal disease, with increased risk of weakening of periodontal ligament and tooth loss. Periodontal ligament is produced and maintained by periodontal ligament fibroblasts (PDLFs). We hypothesized that metabolic dysfunction of PDLFs i...
Autores principales: | Ashour, Amal, Xue, Mingzhan, Al-Motawa, Maryam, Thornalley, Paul J, Rabbani, Naila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594206/ https://www.ncbi.nlm.nih.gov/pubmed/33115819 http://dx.doi.org/10.1136/bmjdrc-2020-001458 |
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