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Pharmacokinetics in routine haemophilia clinical practice: rationale and modalities—a practical review

Prophylactic therapy with exogenous clotting factor concentrates in haemophilia A and B aims to achieve levels of circulating FVIII or FIX that are adequate for the prevention or reduction of spontaneous joint bleeding. Historically, a minimum trough level of at least 1% of the normal levels of circ...

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Detalles Bibliográficos
Autores principales: Hermans, Cedric, Dolan, Gerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594230/
https://www.ncbi.nlm.nih.gov/pubmed/33194165
http://dx.doi.org/10.1177/2040620720966888