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Pharmacokinetics in routine haemophilia clinical practice: rationale and modalities—a practical review
Prophylactic therapy with exogenous clotting factor concentrates in haemophilia A and B aims to achieve levels of circulating FVIII or FIX that are adequate for the prevention or reduction of spontaneous joint bleeding. Historically, a minimum trough level of at least 1% of the normal levels of circ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594230/ https://www.ncbi.nlm.nih.gov/pubmed/33194165 http://dx.doi.org/10.1177/2040620720966888 |