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Intracellular dynamics of Ataxin-2 in the human brains with normal and frontotemporal lobar degeneration with TDP-43 inclusions
TAR DNA-binding protein of 43 kDa (TDP-43) is a major component of intracellular aggregates formed in brains of the patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS), which are correctively referred to as TDP-43 proteinopathies. A link between Ataxin-2 (A...
Autores principales: | Watanabe, Ryohei, Higashi, Shinji, Nonaka, Takashi, Kawakami, Ito, Oshima, Kenichi, Niizato, Kazuhiro, Akiyama, Haruhiko, Yoshida, Mari, Hasegawa, Masato, Arai, Tetsuaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594343/ https://www.ncbi.nlm.nih.gov/pubmed/33115537 http://dx.doi.org/10.1186/s40478-020-01055-9 |
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