Determinants of Ca(2+) release restitution: Insights from genetically altered animals and mathematical modeling

Each heartbeat is followed by a refractory period. Recovery from refractoriness is known as Ca(2+) release restitution (CRR), and its alterations are potential triggers of Ca(2+) arrhythmias. Although the control of CRR has been associated with SR Ca(2+) load and RYR2 Ca(2+) sensitivity, the relativ...

Descripción completa

Detalles Bibliográficos
Autores principales: Cely-Ortiz, Alejandra, Felice, Juan I., Díaz-Zegarra, Leandro A., Valverde, Carlos A., Federico, Marilén, Palomeque, Julieta, Wehrens, Xander H.T., Kranias, Evangelia G., Aiello, Ernesto A., Lascano, Elena C., Negroni, Jorge A., Mattiazzi, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594441/
https://www.ncbi.nlm.nih.gov/pubmed/32986800
http://dx.doi.org/10.1085/jgp.201912512

Ejemplares similares

Ejemplares similares