SAGA–CORE subunit Spt7 is required for correct Ubp8 localization, chromatin association and deubiquitinase activity

BACKGROUND: Histone H2B deubiquitination is performed by numerous deubiquitinases in eukaryotic cells including Ubp8, the catalytic subunit of the tetrameric deubiquitination module (DUBm: Ubp8; Sus1; Sgf11; Sgf73) of the Spt-Ada-Gcn5 acetyltransferase (SAGA). Ubp8 is linked to the rest of SAGA thro...

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Detalles Bibliográficos
Autores principales: Nuño-Cabanes, Carme, García-Molinero, Varinia, Martín-Expósito, Manuel, Gas, María-Eugenia, Oliete-Calvo, Paula, García-Oliver, Encar, de la Iglesia-Vayá, María, Rodríguez-Navarro, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594455/
https://www.ncbi.nlm.nih.gov/pubmed/33115507
http://dx.doi.org/10.1186/s13072-020-00367-3

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