Cargando…
Brown Adipose Expansion and Remission of Glycemic Dysfunction in Obese SM/J Mice
We leverage the SM/J mouse to understand glycemic control in obesity. High-fat-fed SM/J mice initially develop poor glucose homeostasis relative to controls. Strikingly, their glycemic dysfunction resolves by 30 weeks of age despite persistent obesity. The mice dramatically expand their brown adipos...
Autores principales: | Carson, Caryn, Macias-Velasco, Juan F., Gunawardana, Subhadra, Miranda, Mario A., Oyama, Sakura, St. Pierre, Celine L., Schmidt, Heather, Wayhart, Jessica P., Lawson, Heather A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594587/ https://www.ncbi.nlm.nih.gov/pubmed/33027654 http://dx.doi.org/10.1016/j.celrep.2020.108237 |
Ejemplares similares
-
Spontaneous restoration of functional β‐cell mass in obese SM/J mice
por: Miranda, Mario A., et al.
Publicado: (2020) -
Parent-of-origin effects propagate through networks to shape metabolic traits
por: Macias-Velasco, Juan F, et al.
Publicado: (2022) -
Genetic, epigenetic, and environmental mechanisms govern allele-specific gene expression
por: St. Pierre, Celine L., et al.
Publicado: (2022) -
Dietary iron interacts with genetic background to influence glucose homeostasis
por: Miranda, Mario A., et al.
Publicado: (2019) -
Therapeutic value of brown adipose tissue: Correcting metabolic disease through generating healthy fat
por: Gunawardana, Subhadra C.
Publicado: (2012)