Down Syndrome Critical Region 1 Reduces Oxidative Stress–Induced Retinal Ganglion Cells Apoptosis via CREB–Bcl-2 Pathway

PURPOSE: Irreversible retina ganglion cell (RGC) loss is a key process during glaucoma progression. Down syndrome critical region 1 (DSCR1) has been shown to have protective effects against neuronal death. In this study, we aimed to investigate the neuroprotective mechanisms of DSCR1 on RGCs. METHOD...

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Detalles Bibliográficos
Autores principales: Shi, Yuxun, Ye, Dan, Huang, Rong, Xu, Yue, Lu, Peng, Chen, Hailiu, Huang, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594594/
https://www.ncbi.nlm.nih.gov/pubmed/33104163
http://dx.doi.org/10.1167/iovs.61.12.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594594/
https://www.ncbi.nlm.nih.gov/pubmed/33104163
http://dx.doi.org/10.1167/iovs.61.12.23

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