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Divergent Effects of HSP70 Overexpression in Photoreceptors During Inherited Retinal Degeneration

PURPOSE: Disruption of proteostasis is a key event in many neurodegenerative diseases. Heat shock proteins (HSPs) participate in multiple functions associated with intracellular transport and proteostasis. We evaluated the effect of augmented HSP70 expression in mutant photoreceptors of mouse retina...

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Detalles Bibliográficos
Autores principales:	Jiang, Ke, Fairless, Elizabeth, Kanda, Atsuhiro, Gotoh, Norimoto, Cogliati, Tiziana, Li, Tiansen, Swaroop, Anand
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594617/ https://www.ncbi.nlm.nih.gov/pubmed/33107904 http://dx.doi.org/10.1167/iovs.61.12.25

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