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A Blast From the Past: Radiation Therapy During Childhood Causing Cardiac Fibrosis and Calcification Leading to Complete Heart Block
Complete heart block (CHB) in a young patient is a rare phenomenon necessitating an extensive workup to identify the etiology of conduction disturbance. Radiotherapy of the thorax is a known risk factor for cardiomyopathy; however, CHB is a rare complication. Here we present a case of a 46-year-old...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594667/ https://www.ncbi.nlm.nih.gov/pubmed/33133873 http://dx.doi.org/10.7759/cureus.10709 |
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author | Malyshev, Yury Chukwuka, Nnamdi Hashmi, Arsalan Talib Rosanel, Sarah Kulbak, Guy |
author_facet | Malyshev, Yury Chukwuka, Nnamdi Hashmi, Arsalan Talib Rosanel, Sarah Kulbak, Guy |
author_sort | Malyshev, Yury |
collection | PubMed |
description | Complete heart block (CHB) in a young patient is a rare phenomenon necessitating an extensive workup to identify the etiology of conduction disturbance. Radiotherapy of the thorax is a known risk factor for cardiomyopathy; however, CHB is a rare complication. Here we present a case of a 46-year-old man who presented with CHB and was found to have significant cardiac fibrosis and calcification of the mitral valve annulus. His management required a multidisciplinary and multimodality approach to be able to identify childhood radiation as the cause of cardiomyopathy and establish a personalized management strategy with cardiac resynchronization therapy defibrillator. This case highlights radiation therapy as an important cause of cardiac conduction abnormalities even decades later, and the importance of extensive search for other reversible etiologies using the multimodality approach. |
format | Online Article Text |
id | pubmed-7594667 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-75946672020-10-31 A Blast From the Past: Radiation Therapy During Childhood Causing Cardiac Fibrosis and Calcification Leading to Complete Heart Block Malyshev, Yury Chukwuka, Nnamdi Hashmi, Arsalan Talib Rosanel, Sarah Kulbak, Guy Cureus Cardiology Complete heart block (CHB) in a young patient is a rare phenomenon necessitating an extensive workup to identify the etiology of conduction disturbance. Radiotherapy of the thorax is a known risk factor for cardiomyopathy; however, CHB is a rare complication. Here we present a case of a 46-year-old man who presented with CHB and was found to have significant cardiac fibrosis and calcification of the mitral valve annulus. His management required a multidisciplinary and multimodality approach to be able to identify childhood radiation as the cause of cardiomyopathy and establish a personalized management strategy with cardiac resynchronization therapy defibrillator. This case highlights radiation therapy as an important cause of cardiac conduction abnormalities even decades later, and the importance of extensive search for other reversible etiologies using the multimodality approach. Cureus 2020-09-29 /pmc/articles/PMC7594667/ /pubmed/33133873 http://dx.doi.org/10.7759/cureus.10709 Text en Copyright © 2020, Malyshev et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Malyshev, Yury Chukwuka, Nnamdi Hashmi, Arsalan Talib Rosanel, Sarah Kulbak, Guy A Blast From the Past: Radiation Therapy During Childhood Causing Cardiac Fibrosis and Calcification Leading to Complete Heart Block |
title | A Blast From the Past: Radiation Therapy During Childhood Causing Cardiac Fibrosis and Calcification Leading to Complete Heart Block |
title_full | A Blast From the Past: Radiation Therapy During Childhood Causing Cardiac Fibrosis and Calcification Leading to Complete Heart Block |
title_fullStr | A Blast From the Past: Radiation Therapy During Childhood Causing Cardiac Fibrosis and Calcification Leading to Complete Heart Block |
title_full_unstemmed | A Blast From the Past: Radiation Therapy During Childhood Causing Cardiac Fibrosis and Calcification Leading to Complete Heart Block |
title_short | A Blast From the Past: Radiation Therapy During Childhood Causing Cardiac Fibrosis and Calcification Leading to Complete Heart Block |
title_sort | blast from the past: radiation therapy during childhood causing cardiac fibrosis and calcification leading to complete heart block |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594667/ https://www.ncbi.nlm.nih.gov/pubmed/33133873 http://dx.doi.org/10.7759/cureus.10709 |
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