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Antimicrobial Prophylaxis in Clean Pediatric Surgical Procedures: A Necessity or Redundancy?

Background The clinical utility of antimicrobial prophylaxis in clean pediatric surgical cases remains enigmatic. The present study aims to evaluate the prevalence of surgical site infections in instances where antibiotic prophylaxis is not employed prior to clean pediatric surgical procedures. Meth...

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Autores principales: Syed, Muhammad Khalid, Al Faqeeh, Ahmad A, Othman, Alsayed, Hussein, Ahmed A, Rajab, Hala, Hussain, Salman, Zaidi, Syed Muhammad Jawad, Syed, Sabahat K, Syed, Saifullah, Almas, Talal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594672/
https://www.ncbi.nlm.nih.gov/pubmed/33133866
http://dx.doi.org/10.7759/cureus.10701
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author Syed, Muhammad Khalid
Al Faqeeh, Ahmad A
Othman, Alsayed
Hussein, Ahmed A
Rajab, Hala
Hussain, Salman
Zaidi, Syed Muhammad Jawad
Syed, Sabahat K
Syed, Saifullah
Almas, Talal
author_facet Syed, Muhammad Khalid
Al Faqeeh, Ahmad A
Othman, Alsayed
Hussein, Ahmed A
Rajab, Hala
Hussain, Salman
Zaidi, Syed Muhammad Jawad
Syed, Sabahat K
Syed, Saifullah
Almas, Talal
author_sort Syed, Muhammad Khalid
collection PubMed
description Background The clinical utility of antimicrobial prophylaxis in clean pediatric surgical cases remains enigmatic. The present study aims to evaluate the prevalence of surgical site infections in instances where antibiotic prophylaxis is not employed prior to clean pediatric surgical procedures. Methods A retrospective cross-sectional study that included data of all pediatric clean surgical procedures from January 2018 till January 2020 was conducted. All children undergoing clean surgical procedures who did not receive antibiotics at least two weeks prior to the procedure were included in the study. The exclusion criteria included patients with congenital heart disease, ventriculoperitoneal shunt, nephrotic syndrome, immunodeficiency, and prior administration of antimicrobial prophylaxis. All patients were followed for two to four weeks for any signs of surgical site infections. Results Of the 178 patients included, 119 were male and 59 were female, with the mean age hovering at 8.19 ± 2.87 years. Orchidopexy and herniotomy were the most commonly performed surgical procedures, and were performed in 56 (31.46%) and 54 (30.33%) patients, respectively. Only one case of postoperative surgical site wound infection was reported, accounting for a prevalence rate of 0.56%. Conclusion In clean pediatric surgical procedures, the risk of surgical site infections is exceedingly low. The unnecessary use of antibiotics in children can cause deleterious adverse effects and promote antimicrobial resistance. In a carefully selected pediatric population, administration of antibiotic prophylaxis might confer no added benefit.
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spelling pubmed-75946722020-10-31 Antimicrobial Prophylaxis in Clean Pediatric Surgical Procedures: A Necessity or Redundancy? Syed, Muhammad Khalid Al Faqeeh, Ahmad A Othman, Alsayed Hussein, Ahmed A Rajab, Hala Hussain, Salman Zaidi, Syed Muhammad Jawad Syed, Sabahat K Syed, Saifullah Almas, Talal Cureus Internal Medicine Background The clinical utility of antimicrobial prophylaxis in clean pediatric surgical cases remains enigmatic. The present study aims to evaluate the prevalence of surgical site infections in instances where antibiotic prophylaxis is not employed prior to clean pediatric surgical procedures. Methods A retrospective cross-sectional study that included data of all pediatric clean surgical procedures from January 2018 till January 2020 was conducted. All children undergoing clean surgical procedures who did not receive antibiotics at least two weeks prior to the procedure were included in the study. The exclusion criteria included patients with congenital heart disease, ventriculoperitoneal shunt, nephrotic syndrome, immunodeficiency, and prior administration of antimicrobial prophylaxis. All patients were followed for two to four weeks for any signs of surgical site infections. Results Of the 178 patients included, 119 were male and 59 were female, with the mean age hovering at 8.19 ± 2.87 years. Orchidopexy and herniotomy were the most commonly performed surgical procedures, and were performed in 56 (31.46%) and 54 (30.33%) patients, respectively. Only one case of postoperative surgical site wound infection was reported, accounting for a prevalence rate of 0.56%. Conclusion In clean pediatric surgical procedures, the risk of surgical site infections is exceedingly low. The unnecessary use of antibiotics in children can cause deleterious adverse effects and promote antimicrobial resistance. In a carefully selected pediatric population, administration of antibiotic prophylaxis might confer no added benefit. Cureus 2020-09-28 /pmc/articles/PMC7594672/ /pubmed/33133866 http://dx.doi.org/10.7759/cureus.10701 Text en Copyright © 2020, Syed et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Syed, Muhammad Khalid
Al Faqeeh, Ahmad A
Othman, Alsayed
Hussein, Ahmed A
Rajab, Hala
Hussain, Salman
Zaidi, Syed Muhammad Jawad
Syed, Sabahat K
Syed, Saifullah
Almas, Talal
Antimicrobial Prophylaxis in Clean Pediatric Surgical Procedures: A Necessity or Redundancy?
title Antimicrobial Prophylaxis in Clean Pediatric Surgical Procedures: A Necessity or Redundancy?
title_full Antimicrobial Prophylaxis in Clean Pediatric Surgical Procedures: A Necessity or Redundancy?
title_fullStr Antimicrobial Prophylaxis in Clean Pediatric Surgical Procedures: A Necessity or Redundancy?
title_full_unstemmed Antimicrobial Prophylaxis in Clean Pediatric Surgical Procedures: A Necessity or Redundancy?
title_short Antimicrobial Prophylaxis in Clean Pediatric Surgical Procedures: A Necessity or Redundancy?
title_sort antimicrobial prophylaxis in clean pediatric surgical procedures: a necessity or redundancy?
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594672/
https://www.ncbi.nlm.nih.gov/pubmed/33133866
http://dx.doi.org/10.7759/cureus.10701
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