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Hypoxic targeting and activating TH-302 loaded transcatheter arterial embolization microsphere

The tumor-derived and transcatheter arterial chemoembolization (TACE) induced hypoxia microenvironment is closely related to the poor prognosis of hepatocellular carcinoma (HCC). In this study, hypoxia-activated prodrug TH-302 loaded poly(lactic-co-glycolic acid) (PLGA)-based TACE microspheres were...

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Detalles Bibliográficos
Autores principales: Ma, Pengkai, Chen, Jianhua, Qu, Haixian, Li, Ye, Li, Xiaohui, Tang, Xuemei, Song, Zhigang, Xin, Hainan, Zhang, Jinbang, Nai, Jingxue, Li, Zhiping, Wang, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594845/
https://www.ncbi.nlm.nih.gov/pubmed/33096947
http://dx.doi.org/10.1080/10717544.2020.1831102