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Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators
The synthesis and carbonic anhydrase (CA; EC 4.2.1.1) activating effects of a series of oxime ether-based amino alcohols towards four human (h) CA isoforms expressed in human brain, hCA I, II, IV and VII, are described. Most investigated amino alcohol derivatives induced a consistent activation of t...
Autores principales: | Nocentini, Alessio, Cuffaro, Doretta, Ciccone, Lidia, Orlandini, Elisabetta, Nencetti, Susanna, Nuti, Elisa, Rossello, Armando, Supuran, Claudiu T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594847/ https://www.ncbi.nlm.nih.gov/pubmed/33103482 http://dx.doi.org/10.1080/14756366.2020.1838501 |
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