Cargando…

Enhanced oral bioavailability of an etoposide multiple nanoemulsion incorporating a deoxycholic acid derivative–lipid complex

In this study, a system for oral delivery of etoposide (ETP) was designed to avoid the problems associated with low and variable bioavailability of a commercially available ETP emulsion comprised of polyethylene glycol, glycerol, and citric acid anhydrous. ETP was complexed with low-molecular-weight...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jha, Saurav Kumar, Han, Hee-Soo, Subedi, Laxman, Pangeni, Rudra, Chung, Jee Young, Kweon, Seho, Choi, Jeong Uk, Byun, Youngro, Kim, Yong-Hee, Park, Jin Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7594851/ https://www.ncbi.nlm.nih.gov/pubmed/33107339 http://dx.doi.org/10.1080/10717544.2020.1837293

Ejemplares similares

Enhanced oral absorption of pemetrexed by ion-pairing complex formation with deoxycholic acid derivative and multiple nanoemulsion formulations: preparation, characterization, and in vivo oral bioavailability and anticancer effect
por: Pangeni, Rudra, et al.
Publicado: (2018)

Intestinal transport mechanism and in vivo anticancer efficacy of a solid oral formulation incorporating an ion-pairing complex of pemetrexed with deoxycholic acid derivative
por: Pangeni, Rudra, et al.
Publicado: (2019)

Improvements in the Oral Absorption and Anticancer Efficacy of an Oxaliplatin-Loaded Solid Formulation: Pharmacokinetic Properties in Rats and Nonhuman Primates and the Effects of Oral Metronomic Dosing on Colorectal Cancer
por: Pangeni, Rudra, et al.
Publicado: (2020)

Metronomic delivery of orally available pemetrexed-incorporated colloidal dispersions for boosting tumor-specific immunity
por: Maharjan, Ruby, et al.
Publicado: (2021)

Preparation and in vivo evaluation of a topical hydrogel system incorporating highly skin-permeable growth factors, quercetin, and oxygen carriers for enhanced diabetic wound-healing therapy
por: Jee, Jun-Pil, et al.
Publicado: (2019)

Enhancement of the anticancer effect of atorvastatin-loaded nanoemulsions by improving oral absorption via multivalent intestinal transporter-targeting lipids
por: Subedi, Laxman, et al.
Publicado: (2022)

Multiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluation
por: Pangeni, Rudra, et al.
Publicado: (2016)

Anti-Angiogenic Effect of Orally Available Pemetrexed for Metronomic Chemotherapy
por: Maharjan, Ruby, et al.
Publicado: (2019)

Design of chimeric GLP-1A using oligomeric bile acids to utilize transporter-mediated endocytosis for oral delivery
por: Kweon, Seho, et al.
Publicado: (2023)

Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex
por: Hwang, Seung Rim, et al.
Publicado: (2016)

Improvement of colchicine oral bioavailability by incorporating eugenol in the nanoemulsion as an oil excipient and enhancer
por: Shen, Qi, et al.
Publicado: (2011)

Preparation of Topical Itraconazole with Enhanced Skin/Nail Permeability and In Vivo Antifungal Efficacy against Superficial Mycosis
por: Subedi, Laxman, et al.
Publicado: (2021)

Preparation, Characterization, and In Vivo Evaluation of an Oral Multiple Nanoemulsive System for Co-Delivery of Pemetrexed and Quercetin
por: Pangeni, Rudra, et al.
Publicado: (2018)

Development of Liposome containing sodium deoxycholate to enhance oral bioavailability of itraconazole
por: Li, Zhenbao, et al.
Publicado: (2017)

Formulation and development of Serratiopeptidase enteric coated tablets and analytical method validation by UV Spectroscopy
por: Panthi, Vijay Kumar, et al.
Publicado: (2021)

The effect of food and concurrent chemotherapy on the bioavailability of oral etoposide.
por: Harvey, V. J., et al.
Publicado: (1985)

Excipient Nanoemulsions for Improving Oral Bioavailability of Bioactives
por: Salvia-Trujillo, Laura, et al.
Publicado: (2016)

Reduction of atherosclerotic lesions in rabbits treated with etoposide associated with cholesterol-rich nanoemulsions
por: Tavares, Elaine R, et al.
Publicado: (2011)

Formulation and characterization of Cefuroxime Axetil nanoemulsion for improved bioavailability
por: Patel, Yomesh, et al.
Publicado: (2012)

Nanoemulsion: An Emerging Novel Technology for Improving the Bioavailability of Drugs
por: Preeti, et al.
Publicado: (2023)

Cytotoxicity Evaluation of Turmeric Extract Incorporated Oil-in-Water Nanoemulsion
por: Yoon, Hee Jeong, et al.
Publicado: (2018)

Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid
por: Majimbi, Maimuna, et al.
Publicado: (2021)

Topical formulation of sodium deoxycholate for submental lipolysis
por: Park, Hye Jeong, et al.
Publicado: (2023)

Nanoemulsion and Nanoliposome Based Strategies for Improving Anthocyanin Stability and Bioavailability
por: Chen, Bing-Huei, et al.
Publicado: (2019)

Development and characterisation of ibuprofen-loaded nanoemulsion with enhanced oral bioavailability
por: Anuar, Nurfazreen, et al.
Publicado: (2020)

Absorption and Bioavailability of Novel UltraShear Nanoemulsion of Cannabidiol in Rats
por: ElSohly, Mahmoud A., et al.
Publicado: (2023)

Nanoemulsion improves the oral bioavailability of baicalin in rats: in vitro and in vivo evaluation
por: Zhao, Ling, et al.
Publicado: (2013)

Nanoemulsions for Enhancement of Curcumin Bioavailability and Their Safety Evaluation: Effect of Emulsifier Type
por: Gonçalves, Raquel F. S., et al.
Publicado: (2021)

Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham
por: Kim, Seung Wook, et al.
Publicado: (2017)

Skin permeation mechanism and bioavailability enhancement of celecoxib from transdermally applied nanoemulsion
por: Shakeel, Faiyaz, et al.
Publicado: (2008)

Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide
por: Yen, Ching-Chi, et al.
Publicado: (2018)

Etoposide Amorphous Nanopowder for Improved Oral Bioavailability: Formulation Development, Optimization, in vitro and in vivo Evaluation
por: Wang, Yue, et al.
Publicado: (2020)

Encapsulation of Lipid-Soluble Bioactives by Nanoemulsions
por: Banasaz, Shahin, et al.
Publicado: (2020)

Enhanced oral bioavailability and bioefficacy of phloretin using mixed polymeric modified self‐nanoemulsions
por: Wang, Yiling, et al.
Publicado: (2020)

Nanoemulsions as delivery systems for lipophilic nutraceuticals: strategies for improving their formulation, stability, functionality and bioavailability
por: Choi, Seung Jun, et al.
Publicado: (2020)

Intranasal delivery of Clozapine using nanoemulsion-based in-situ gels: An approach for bioavailability enhancement
por: Abdulla, Nourhan A., et al.
Publicado: (2021)

The Effect of Deoxycholic Acid on Secretion and Motility in the Rat and Guinea Pig Large Intestine
por: Kim, Nam Hee, et al.
Publicado: (2017)

Successful Treatment of Protothecal Tenosynovitis in an Immunocompetent Patient using Amphotericin B Deoxycholate
por: Kim, Ji-Eun, et al.
Publicado: (2017)

Preparation, Characterization, and Antioxidant Activity of Nanoemulsions Incorporating Lemon Essential Oil
por: Liu, Ting, et al.
Publicado: (2022)

Preparation, characterization, and antimicrobial activity of nanoemulsions incorporating citral essential oil
por: Lu, Wen-Chien, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lrbjnokc946jhdufh6vlimtuf3