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Persistent abnormal muscle response after microvascular decompression for hemifacial spasm
To explore the causes of persistent abnormal muscle response (AMR) after microvascular decompression (MVD) for hemifacial spasm (HFS) and the clinical outcomes of these patients. MVDs performed in Nanjing Drum Tower Hospital in 2017 were retrospectively studied, and 326 patients with HFS were classi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595092/ https://www.ncbi.nlm.nih.gov/pubmed/33116255 http://dx.doi.org/10.1038/s41598-020-75742-x |
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author | Xu, Li Xu, Wu Wang, Jing Chong, Yulong Liang, Weibang Jiang, Chengrong |
author_facet | Xu, Li Xu, Wu Wang, Jing Chong, Yulong Liang, Weibang Jiang, Chengrong |
author_sort | Xu, Li |
collection | PubMed |
description | To explore the causes of persistent abnormal muscle response (AMR) after microvascular decompression (MVD) for hemifacial spasm (HFS) and the clinical outcomes of these patients. MVDs performed in Nanjing Drum Tower Hospital in 2017 were retrospectively studied, and 326 patients with HFS were classified into two groups based on whether AMR disappeared or persisted following MVD. The clinical features, treatment efficacy and postoperative complications were compared between the two groups. 305 patients with disappeared AMR after decompression were classified as Group A. In Group B, the 21 patients exhibited persistent AMR after successful MVD. The preoperative duration of symptoms in Group B was significantly longer than that in Group A (P < 0.001), and no significant difference was identified between the two groups in terms of gender, side, age and offending vessels (P > 0.05). The immediate postoperative cure rate of Group A (88.9%)was significantly higher than that in Group B (28.6%, P < 0.001), furthermore, the two groups were not different in the long-term outcome and the incidence of surgical complications (P > 0.05). The long preoperative duration of HFS patients may account for persistent AMR after successful decompression, and it is more likely for these patients to get delayed cured, the long-term outcomes showed no difference compared to those in patients with disappeared AMR after MVD. |
format | Online Article Text |
id | pubmed-7595092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-75950922020-10-29 Persistent abnormal muscle response after microvascular decompression for hemifacial spasm Xu, Li Xu, Wu Wang, Jing Chong, Yulong Liang, Weibang Jiang, Chengrong Sci Rep Article To explore the causes of persistent abnormal muscle response (AMR) after microvascular decompression (MVD) for hemifacial spasm (HFS) and the clinical outcomes of these patients. MVDs performed in Nanjing Drum Tower Hospital in 2017 were retrospectively studied, and 326 patients with HFS were classified into two groups based on whether AMR disappeared or persisted following MVD. The clinical features, treatment efficacy and postoperative complications were compared between the two groups. 305 patients with disappeared AMR after decompression were classified as Group A. In Group B, the 21 patients exhibited persistent AMR after successful MVD. The preoperative duration of symptoms in Group B was significantly longer than that in Group A (P < 0.001), and no significant difference was identified between the two groups in terms of gender, side, age and offending vessels (P > 0.05). The immediate postoperative cure rate of Group A (88.9%)was significantly higher than that in Group B (28.6%, P < 0.001), furthermore, the two groups were not different in the long-term outcome and the incidence of surgical complications (P > 0.05). The long preoperative duration of HFS patients may account for persistent AMR after successful decompression, and it is more likely for these patients to get delayed cured, the long-term outcomes showed no difference compared to those in patients with disappeared AMR after MVD. Nature Publishing Group UK 2020-10-28 /pmc/articles/PMC7595092/ /pubmed/33116255 http://dx.doi.org/10.1038/s41598-020-75742-x Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Xu, Li Xu, Wu Wang, Jing Chong, Yulong Liang, Weibang Jiang, Chengrong Persistent abnormal muscle response after microvascular decompression for hemifacial spasm |
title | Persistent abnormal muscle response after microvascular decompression for hemifacial spasm |
title_full | Persistent abnormal muscle response after microvascular decompression for hemifacial spasm |
title_fullStr | Persistent abnormal muscle response after microvascular decompression for hemifacial spasm |
title_full_unstemmed | Persistent abnormal muscle response after microvascular decompression for hemifacial spasm |
title_short | Persistent abnormal muscle response after microvascular decompression for hemifacial spasm |
title_sort | persistent abnormal muscle response after microvascular decompression for hemifacial spasm |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595092/ https://www.ncbi.nlm.nih.gov/pubmed/33116255 http://dx.doi.org/10.1038/s41598-020-75742-x |
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