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Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels
Dyslipidemia is the primary cause of cardiovascular disease, which is a serious human health problem in large parts of the world. Therefore, it is important to understand the genetic and molecular mechanisms that regulate blood levels of cholesterol and other lipids. Discovery of genetic elements in...
Autores principales: | Zhang, Qianqian, Cai, Zexi, Lhomme, Marie, Sahana, Goutam, Lesnik, Philippe, Guerin, Maryse, Fredholm, Merete, Karlskov-Mortensen, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595098/ https://www.ncbi.nlm.nih.gov/pubmed/33116219 http://dx.doi.org/10.1038/s41598-020-75612-6 |
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