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Nuclear FOXP3 inhibits tumor growth and induced apoptosis in hepatocellular carcinoma by targeting c-Myc

The status of FOXP3 and its isoforms in hepatocellular carcinoma (HCC) is unclear. We aimed to investigate the expression and function of FOXP3 and its isoforms in HCC. The study was performed on 84 HCC patients, HCC cell lines and a mouse tumor model. The levels of FOXP3 and its isoforms were deter...

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Detalles Bibliográficos
Autores principales: Gong, Zhongqin, Jia, Hao, Yu, Jianqing, Liu, Yi, Ren, Jianwei, Yang, Shengli, Hu, Baoguang, Liu, Liping, Lai, Paul B. S., Chen, George Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595121/
https://www.ncbi.nlm.nih.gov/pubmed/33116119
http://dx.doi.org/10.1038/s41389-020-00283-x

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