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YAP and TAZ protect against white adipocyte cell death during obesity

The expansion of the white adipose tissue (WAT) in obesity goes along with increased mechanical, metabolic and inflammatory stress. How adipocytes resist this stress is still poorly understood. Both in human and mouse adipocytes, the transcriptional co-activators YAP/TAZ and YAP/TAZ target genes bec...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Wang, ShengPeng, Shi, Yue, Li, Rui, Günther, Stefan, Ong, Yu Ting, Potente, Michael, Yuan, Zuyi, Liu, Enqi, Offermanns, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595161/
https://www.ncbi.nlm.nih.gov/pubmed/33116140
http://dx.doi.org/10.1038/s41467-020-19229-3