Mesenchymal stem cells promote metastasis through activation of an ABL-MMP9 signaling axis in lung cancer cells

Mesenchymal stem cells (MSCs) are recruited and activated by solid tumors and play a role in tumor progression and metastasis. Here we show that MSCs promote metastasis in a panel of non-small cell lung cancer (NSCLC) cells. MSCs elicit transcriptional alterations in lung cancer cells leading to inc...

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Detalles Bibliográficos
Autores principales: Gu, Jing Jin, Hoj, Jacob, Rouse, Clay, Pendergast, Ann Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595271/
https://www.ncbi.nlm.nih.gov/pubmed/33119681
http://dx.doi.org/10.1371/journal.pone.0241423

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