Test-statistic inflation in methylome-wide association studies

Recent years have seen a surge of methylome-wide association studies (MWAS). We observed that many of these studies suffer from test statistic inflation that is most likely caused by commonly used quality control (QC) pipelines not going far enough to remove technical artefacts. To support this clai...

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Detalles Bibliográficos
Autores principales: Guintivano, Jerry, Shabalin, Andrey A, Chan, Robin F., Rubinow, David R., Sullivan, Patrick F., Meltzer-Brody, Samantha, Aberg, Karolina a, van den Oord, Edwin J. C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595582/
https://www.ncbi.nlm.nih.gov/pubmed/32425094
http://dx.doi.org/10.1080/15592294.2020.1758382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595582/
https://www.ncbi.nlm.nih.gov/pubmed/32425094
http://dx.doi.org/10.1080/15592294.2020.1758382

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