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Test-statistic inflation in methylome-wide association studies
Recent years have seen a surge of methylome-wide association studies (MWAS). We observed that many of these studies suffer from test statistic inflation that is most likely caused by commonly used quality control (QC) pipelines not going far enough to remove technical artefacts. To support this clai...
Autores principales: | Guintivano, Jerry, Shabalin, Andrey A, Chan, Robin F., Rubinow, David R., Sullivan, Patrick F., Meltzer-Brody, Samantha, Aberg, Karolina a, van den Oord, Edwin J. C. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595582/ https://www.ncbi.nlm.nih.gov/pubmed/32425094 http://dx.doi.org/10.1080/15592294.2020.1758382 |
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