IAP inhibitor, Embelin increases VCAM-1 levels on the endothelium, producing lymphocytic infiltration and antitumor immunity

There is an increasing unmet need for successful immunotherapeutic interventions. Lymphocyte extravasation via tumor tissue endothelial cells (TECs) is required for lymphocyte infiltration into tumor sites. This study aimed to investigate the clinical significance of dysfunctional TECs in pancreatic...

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Detalles Bibliográficos
Autores principales: Nakajima, Kosei, Ino, Yoshinori, Yamazaki-Itoh, Rie, Naito, Chie, Shimasaki, Mari, Takahashi, Mami, Esaki, Minoru, Nara, Satoshi, Kishi, Yoji, Shimada, Kazuaki, Hiraoka, Nobuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595596/
https://www.ncbi.nlm.nih.gov/pubmed/33178497
http://dx.doi.org/10.1080/2162402X.2020.1838812

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