Podocytes maintain high basal levels of autophagy independent of mtor signaling

While constant basal levels of macroautophagy/autophagy are a prerequisite to preserve long-lived podocytes at the filtration barrier, MTOR regulates at the same time podocyte size and compensatory hypertrophy. Since MTOR is known to generally suppress autophagy, the apparently independent regulatio...

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Detalles Bibliográficos
Autores principales: Bork, Tillmann, Liang, Wei, Yamahara, Kosuke, Lee, Philipp, Tian, Zhejia, Liu, Shuya, Schell, Christoph, Thedieck, Kathrin, Hartleben, Bjoern, Patel, Ketan, Tharaux, Pierre-Louis, Lenoir, Olivia, Huber, Tobias B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper - Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595647/
https://www.ncbi.nlm.nih.gov/pubmed/31865844
http://dx.doi.org/10.1080/15548627.2019.1705007

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