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Age-dependent degeneration of an identified adult leg motor neuron in a Drosophila SOD1 model of ALS

Mutations in superoxide dismutase 1 (SOD1) cause familial amyotrophic lateral sclerosis (ALS) in humans. ALS is a neurodegenerative disease characterized by progressive motor neuron loss leading to paralysis and inevitable death in affected individuals. Using a gene replacement strategy to introduce...

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Detalles Bibliográficos
Autores principales:	Agudelo, Anthony, St. Amand, Victoria, Grissom, Lindsey, Lafond, Danielle, Achilli, Toni, Sahin, Asli, Reenan, Robert, Stilwell, Geoff
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595701/ https://www.ncbi.nlm.nih.gov/pubmed/32994185 http://dx.doi.org/10.1242/bio.049692

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