Limbic Encephalitis as a Heralding Manifestation of Primary Sjogren’s Syndrome

Sjogren’s syndrome (SS) is an autoimmune disorder characterized by lymphocytic and plasma cell infiltration of exocrine glands, resulting in dry mouth and keratoconjunctivitis sicca. The clinical symptoms may range from mucosal dryness to more systemic complaints. We report a 42-year-old man present...

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Autores principales: Verma, Rajesh, Anand, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595785/
https://www.ncbi.nlm.nih.gov/pubmed/33144809
http://dx.doi.org/10.1055/s-0040-1715997
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author Verma, Rajesh
Anand, Rohit
author_facet Verma, Rajesh
Anand, Rohit
author_sort Verma, Rajesh
collection PubMed
description Sjogren’s syndrome (SS) is an autoimmune disorder characterized by lymphocytic and plasma cell infiltration of exocrine glands, resulting in dry mouth and keratoconjunctivitis sicca. The clinical symptoms may range from mucosal dryness to more systemic complaints. We report a 42-year-old man presenting with rapid cognitive decline and memory impairment for 2 months. Magnetic resonance imaging of the cranium revealed abnormal signals at the bilateral medial temporal lobe and hippocampal region. The autoimmune panel and paraneoplastic antibodies were negative. The patient was labeled as a case of primary SS based on the vasculitis profile and pathological examination of lip biopsy. This case illustrates a rare, heralding manifestation of SS as limbic encephalitis.
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spelling pubmed-75957852020-11-02 Limbic Encephalitis as a Heralding Manifestation of Primary Sjogren’s Syndrome Verma, Rajesh Anand, Rohit J Neurosci Rural Pract Sjogren’s syndrome (SS) is an autoimmune disorder characterized by lymphocytic and plasma cell infiltration of exocrine glands, resulting in dry mouth and keratoconjunctivitis sicca. The clinical symptoms may range from mucosal dryness to more systemic complaints. We report a 42-year-old man presenting with rapid cognitive decline and memory impairment for 2 months. Magnetic resonance imaging of the cranium revealed abnormal signals at the bilateral medial temporal lobe and hippocampal region. The autoimmune panel and paraneoplastic antibodies were negative. The patient was labeled as a case of primary SS based on the vasculitis profile and pathological examination of lip biopsy. This case illustrates a rare, heralding manifestation of SS as limbic encephalitis. Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-10 2020-09-04 /pmc/articles/PMC7595785/ /pubmed/33144809 http://dx.doi.org/10.1055/s-0040-1715997 Text en Association for Helping Neurosurgical Sick People. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. https://creativecommons.org/licenses/by-nc-nd/4.0/. https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Verma, Rajesh
Anand, Rohit
Limbic Encephalitis as a Heralding Manifestation of Primary Sjogren’s Syndrome
title Limbic Encephalitis as a Heralding Manifestation of Primary Sjogren’s Syndrome
title_full Limbic Encephalitis as a Heralding Manifestation of Primary Sjogren’s Syndrome
title_fullStr Limbic Encephalitis as a Heralding Manifestation of Primary Sjogren’s Syndrome
title_full_unstemmed Limbic Encephalitis as a Heralding Manifestation of Primary Sjogren’s Syndrome
title_short Limbic Encephalitis as a Heralding Manifestation of Primary Sjogren’s Syndrome
title_sort limbic encephalitis as a heralding manifestation of primary sjogren’s syndrome
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595785/
https://www.ncbi.nlm.nih.gov/pubmed/33144809
http://dx.doi.org/10.1055/s-0040-1715997
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