Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome

Cannabinoids have been found to be effective in controlling seizures and the highly purified form of cannabinoid derived for Cannabis sativa . Cannabidiol (CBD) is now approved for Lennox–Gastaut syndrome (LGS) and Dravet syndrome. CBD was used in a 9-year-old boy with LGS (unknown etiology) with ve...

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Autor principal: Prakash, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595804/
https://www.ncbi.nlm.nih.gov/pubmed/33144805
http://dx.doi.org/10.1055/s-0040-1714329
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author Prakash, Vikram
author_facet Prakash, Vikram
author_sort Prakash, Vikram
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description Cannabinoids have been found to be effective in controlling seizures and the highly purified form of cannabinoid derived for Cannabis sativa . Cannabidiol (CBD) is now approved for Lennox–Gastaut syndrome (LGS) and Dravet syndrome. CBD was used in a 9-year-old boy with LGS (unknown etiology) with very good results. The electroencephalography (EEG) response was very dramatic with near normalization of EEG background and complete control of seizures. The effect of CBD on EEG with such an improvement has not been described previously. Also, this adds to evidence that early intervention in LGS with CBD might be more helpful and improve outcomes.
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spelling pubmed-75958042020-11-02 Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome Prakash, Vikram J Neurosci Rural Pract Cannabinoids have been found to be effective in controlling seizures and the highly purified form of cannabinoid derived for Cannabis sativa . Cannabidiol (CBD) is now approved for Lennox–Gastaut syndrome (LGS) and Dravet syndrome. CBD was used in a 9-year-old boy with LGS (unknown etiology) with very good results. The electroencephalography (EEG) response was very dramatic with near normalization of EEG background and complete control of seizures. The effect of CBD on EEG with such an improvement has not been described previously. Also, this adds to evidence that early intervention in LGS with CBD might be more helpful and improve outcomes. Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-10 2020-08-11 /pmc/articles/PMC7595804/ /pubmed/33144805 http://dx.doi.org/10.1055/s-0040-1714329 Text en Association for Helping Neurosurgical Sick People. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. https://creativecommons.org/licenses/by-nc-nd/4.0/. https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Prakash, Vikram
Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome
title Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome
title_full Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome
title_fullStr Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome
title_full_unstemmed Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome
title_short Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome
title_sort effect of cannabinoids on electroencephalography of a child with lennox–gastaut syndrome
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595804/
https://www.ncbi.nlm.nih.gov/pubmed/33144805
http://dx.doi.org/10.1055/s-0040-1714329
work_keys_str_mv AT prakashvikram effectofcannabinoidsonelectroencephalographyofachildwithlennoxgastautsyndrome

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