Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to induce chromatin opening

Type II DNA topoisomerases (topo II) flip the spatial positions of two DNA duplexes, called G- and T- segments, by a cleavage-passage-resealing mechanism. In living cells, these DNA segments can be derived from distant sites on the same chromosome. Due to lack of proper methodology, however, no dire...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyaji, Mary, Furuta, Ryohei, Hosoya, Osamu, Sano, Kuniaki, Hara, Norikazu, Kuwano, Ryozo, Kang, Jiyoung, Tateno, Masaru, Tsutsui, Kimiko M., Tsutsui, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596052/
https://www.ncbi.nlm.nih.gov/pubmed/33122676
http://dx.doi.org/10.1038/s41598-020-75004-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596052/
https://www.ncbi.nlm.nih.gov/pubmed/33122676
http://dx.doi.org/10.1038/s41598-020-75004-w

Ejemplares similares