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Topoisomerase IIβ targets DNA crossovers formed between distant homologous sites to induce chromatin opening
Type II DNA topoisomerases (topo II) flip the spatial positions of two DNA duplexes, called G- and T- segments, by a cleavage-passage-resealing mechanism. In living cells, these DNA segments can be derived from distant sites on the same chromosome. Due to lack of proper methodology, however, no dire...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596052/ https://www.ncbi.nlm.nih.gov/pubmed/33122676 http://dx.doi.org/10.1038/s41598-020-75004-w |