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Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesothelioma

Malignant pleural mesothelioma (MPM) is a rare, but aggressive tumor with dismal prognosis. Platinum-based chemotherapy is regularly used as part of multimodality therapy. The expression of metallothioneins (MT) has been identified as a reason for cisplatin resistance, which often leads to early the...

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Detalles Bibliográficos
Autores principales:	Borchert, Sabrina, Suckrau, Pia-Maria, Walter, Robert F. H., Wessolly, Michael, Mairinger, Elena, Steinborn, Julia, Hegedus, Balazs, Hager, Thomas, Herold, Thomas, Eberhardt, Wilfried E. E., Wohlschlaeger, Jeremias, Aigner, Clemens, Bankfalvi, Agnes, Schmid, Kurt Werner, Mairinger, Fabian D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596082/ https://www.ncbi.nlm.nih.gov/pubmed/33122816 http://dx.doi.org/10.1038/s41598-020-75807-x

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