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Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function

Zbtb11 is a conserved transcription factor mutated in families with hereditary intellectual disability. Its precise molecular and cellular functions are currently unknown, precluding our understanding of the aetiology of this disease. Using a combination of functional genomics, genetic and biochemic...

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Detalles Bibliográficos
Autores principales: Wilson, Brooke C., Boehme, Lena, Annibali, Ambra, Hodgkinson, Alan, Carroll, Thomas S., Oakey, Rebecca J., Seitan, Vlad C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596099/
https://www.ncbi.nlm.nih.gov/pubmed/33122634
http://dx.doi.org/10.1038/s41467-020-19205-x