Cargando…

Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function

Zbtb11 is a conserved transcription factor mutated in families with hereditary intellectual disability. Its precise molecular and cellular functions are currently unknown, precluding our understanding of the aetiology of this disease. Using a combination of functional genomics, genetic and biochemic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wilson, Brooke C., Boehme, Lena, Annibali, Ambra, Hodgkinson, Alan, Carroll, Thomas S., Oakey, Rebecca J., Seitan, Vlad C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596099/ https://www.ncbi.nlm.nih.gov/pubmed/33122634 http://dx.doi.org/10.1038/s41467-020-19205-x

Ejemplares similares

Nuclear genetic regulation of the human mitochondrial transcriptome
por: Ali, Aminah T, et al.
Publicado: (2019)

The ets-Related Transcription Factor GABP Directs Bidirectional Transcription
por: Collins, Patrick J, et al.
Publicado: (2007)

Ets transcription factor GABP controls T cell homeostasis and immunity
por: Luo, Chong T., et al.
Publicado: (2017)

GABPα and CREB1 Binding to Double Nucleotide Polymorphisms of Their Consensus Motifs and Cooperative Binding to the Composite ETS ⇔ CRE Motif (ACCGGAAGTGACGTCA)
por: Assad, Nima, et al.
Publicado: (2019)

Decreased expression of BRCA1 in SK-BR-3 cells is the result of aberrant activation of the GABP Beta promoter by an NRF-1-containing complex
por: Thompson, Crista, et al.
Publicado: (2011)

GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer
por: McKinney, Andrew M., et al.
Publicado: (2022)

Overlapping ETS and CRE Motifs ((G)/(C)CGGAAGTGACGTCA) Preferentially Bound by GABPα and CREB Proteins
por: Chatterjee, Raghunath, et al.
Publicado: (2012)

KIF11 microdeletion is associated with microcephaly, chorioretinopathy and intellectual disability
por: Malvezzi, João VM, et al.
Publicado: (2018)

Intellectual disability and antipsychotics
por: Iñiguez, I. Cuevas, et al.
Publicado: (2021)

Remote Training of Dental Students and Professionals to Promote Cooperative Behavior in Patients with Intellectual and Developmental Disabilities
por: Matteucci, Marissa, et al.
Publicado: (2022)

The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer
por: Sharma, Naomi L., et al.
Publicado: (2014)

GABPα Binding to Overlapping ETS and CRE DNA Motifs Is Enhanced by CREB1: Custom DNA Microarrays
por: He, Ximiao, et al.
Publicado: (2015)

Commentary: The unliganded glucocorticoid receptor positively regulates the tumor suppressor gene BRCA1 through GABP beta
por: Polansky, Hanan, et al.
Publicado: (2015)

ZBTB11 dysfunction: spectrum of brain abnormalities, biochemical signature and cellular consequences
por: Sumathipala, Dulika, et al.
Publicado: (2022)

Mutational profile of ZBTB16‐RARA‐positive acute myeloid leukemia
por: Fabiani, Emiliano, et al.
Publicado: (2021)

Regulation of mutant TERT by BRAF V600E/MAP kinase pathway through FOS/GABP in human cancer
por: Liu, Rengyun, et al.
Publicado: (2018)

Intellectual disabilities and yoga
por: Singh, Satendra
Publicado: (2013)

Anesthesia for intellectually disabled
por: Chaudhary, Kapil, et al.
Publicado: (2017)

Intellectual Disability and Parenthood
por: Kandel, Isack, et al.
Publicado: (2005)

Nymphomania with intellectual disability
por: Sharma, Mini, et al.
Publicado: (2022)

The Genetics of Intellectual Disability
por: Jansen, Sandra, et al.
Publicado: (2023)

HCFC1 is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1, and GABP transcription factor occupancy
por: Michaud, Joëlle, et al.
Publicado: (2013)

Model of Intellectual Disability and the Relationship of Attitudes Towards the Sexuality of Persons with an Intellectual Disability
por: Parchomiuk, Monika
Publicado: (2012)

BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription
por: Dias, Cristina, et al.
Publicado: (2016)

Biallelic loss-of-function variants in WDR11 are associated with microcephaly and intellectual disability
por: Haag, Natja, et al.
Publicado: (2021)

11p11.12p12 duplication in a family with intellectual disability and craniofacial anomalies
por: Chen, Xuejiao, et al.
Publicado: (2021)

Biallelic ZBTB11 variants associated with complex neuropsychiatric phenotype featuring Tourette syndrome
por: Scala, Marcello, et al.
Publicado: (2022)

Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy
por: Boogerd, Cornelis J, et al.
Publicado: (2022)

Caregiving, intellectual disability, and dementia: Report of the Summit Workgroup on Caregiving and Intellectual and Developmental Disabilities
por: Heller, Tamar, et al.
Publicado: (2018)

Dental treatment under general anesthesia in an intellectually disabled child with intellectually disabled parents
por: Han, Jeong-Hwa, et al.
Publicado: (2016)

Formal Caregivers in Intellectual Disability Facilities
por: Martins, B., et al.
Publicado: (2023)

Diet quality among people with intellectual disabilities and borderline intellectual functioning
por: Gast, David A. A., et al.
Publicado: (2021)

BTB/POZ zinc finger protein ZBTB16 inhibits breast cancer proliferation and metastasis through upregulating ZBTB28 and antagonizing BCL6/ZBTB27
por: He, Jin, et al.
Publicado: (2020)

The Health of People with Intellectual Disability
por: Lennox, Nicholas, et al.
Publicado: (2011)

Intellectual and Developmental Disabilities: Eugenics
por: Grenon, Ingrid, et al.
Publicado: (2014)

Autosomal dominant intellectual disability
por: Wieczorek, Dagmar
Publicado: (2018)

Adult neurogenesis in intellectual disabilities
por: Allegra, Manuela, et al.
Publicado: (2017)

Commentary: The origins of intellectual disability
por: Plomin, Robert
Publicado: (2022)

Empowering people with intellectual disability
por: Skuse, David
Publicado: (2011)

Intellectual disability: an Italian perspective
por: La Malfa, Giampaolo, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_pot0irff3hjjauibuupr5ncg50