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New nanocarried phenobarbital formulation: Maintains better control of pentylenetetrazole-Induced seizures

This study aims to evaluate the efficacy of slow release phenobarbital in the control of convulsions triggered by pentylenetetrazole (PTZ), verifying the time of permanence in the anticonvulsant effect through behavior and electroencephalographic records. A total of 162 male Wistar rats weighing bet...

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Detalles Bibliográficos
Autores principales: de Almeida, Lorena Cristina Nunes, de Andrade Marques, Beatriz, Silva, Rafaela Laranjeira, Hamoy, Akira Otake, de Mello, Vanessa Jóia, Borges, Rosivaldo dos Santos, Brito, Frank Sales Nunes, Longo, Elson, Anicete-Santos, Marcos, Hamoy, Moisés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596104/
https://www.ncbi.nlm.nih.gov/pubmed/33145190
http://dx.doi.org/10.1016/j.btre.2020.e00539