Pharmacological Targeting of CSF1R Inhibits Microglial Proliferation and Aggravates the Progression of Cerebral Ischemic Pathology

Ischemic stroke can induce rapid activation of the microglia. It has been reported that the microglia’s survival is dependent on colony-stimulating factor 1 receptor (CSF1R) signaling and that pharmacological inhibition of CSF1R leads to morphological changes in the microglia in the healthy brain. H...

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Detalles Bibliográficos
Autores principales: Hou, Boru, Jiang, Cheng, Wang, Dong, Wang, Gang, Wang, Zening, Zhu, Miaojuan, Kang, Yuchen, Su, Jiacheng, Wei, Pengfei, Ren, Haijun, Ju, Furong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596178/
https://www.ncbi.nlm.nih.gov/pubmed/33177990
http://dx.doi.org/10.3389/fncel.2020.00267

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