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MPL Adjuvant Contains Competitive Antagonists of Human TLR4

Monophosphoryl lipid A (MPL(®)) is the first non-alum vaccine adjuvant to achieve widespread clinical and market acceptance, a remarkable achievement given that it is manufactured from a Salmonella enterica endotoxin. To understand how MPL(®) successfully balanced the dual mandate of vaccine design—...

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Detalles Bibliográficos
Autores principales:	Wang, Yi-Qi, Bazin-Lee, Hélène, Evans, Jay T., Casella, Carolyn R., Mitchell, Thomas C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596181/ https://www.ncbi.nlm.nih.gov/pubmed/33178204 http://dx.doi.org/10.3389/fimmu.2020.577823

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