Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation

A 73-year-old man with a history of type 2 diabetes mellitus, nephrolithiasis, and recurrent urinary tract infections caused by Candida glabrata was admitted to our hospital. Urosepsis was diagnosed and C. glabrata was isolated from urine and blood cultures. Computed tomography intravenous pyelograp...

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Autores principales: van Merode, N.A.M., Pat, J.J., Wolfhagen, M.J.H.M., Dijkstra, G.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Inflammation and Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596195/
https://www.ncbi.nlm.nih.gov/pubmed/33145176
http://dx.doi.org/10.1016/j.eucr.2020.101468
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author van Merode, N.A.M.
Pat, J.J.
Wolfhagen, M.J.H.M.
Dijkstra, G.A.
author_facet van Merode, N.A.M.
Pat, J.J.
Wolfhagen, M.J.H.M.
Dijkstra, G.A.
author_sort van Merode, N.A.M.
collection PubMed
description A 73-year-old man with a history of type 2 diabetes mellitus, nephrolithiasis, and recurrent urinary tract infections caused by Candida glabrata was admitted to our hospital. Urosepsis was diagnosed and C. glabrata was isolated from urine and blood cultures. Computed tomography intravenous pyelography (CT-IVP) revealed bilateral filling defects caused by renal fungal balls. Treatment initially comprised intravenous anidulafungin coupled with continuous local anidulafungin irrigation via bilateral nephrostomy tubes, which was followed by high-dose oral fluconazole. This regimen successfully eradicated the C. glabrata in follow-up cultures.
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spelling pubmed-75961952020-11-02 Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation van Merode, N.A.M. Pat, J.J. Wolfhagen, M.J.H.M. Dijkstra, G.A. Urol Case Rep Inflammation and Infection A 73-year-old man with a history of type 2 diabetes mellitus, nephrolithiasis, and recurrent urinary tract infections caused by Candida glabrata was admitted to our hospital. Urosepsis was diagnosed and C. glabrata was isolated from urine and blood cultures. Computed tomography intravenous pyelography (CT-IVP) revealed bilateral filling defects caused by renal fungal balls. Treatment initially comprised intravenous anidulafungin coupled with continuous local anidulafungin irrigation via bilateral nephrostomy tubes, which was followed by high-dose oral fluconazole. This regimen successfully eradicated the C. glabrata in follow-up cultures. Elsevier 2020-10-26 /pmc/articles/PMC7596195/ /pubmed/33145176 http://dx.doi.org/10.1016/j.eucr.2020.101468 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Inflammation and Infection
van Merode, N.A.M.
Pat, J.J.
Wolfhagen, M.J.H.M.
Dijkstra, G.A.
Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation
title Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation
title_full Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation
title_fullStr Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation
title_full_unstemmed Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation
title_short Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation
title_sort successfully treated bilateral renal fungal balls with continuous anidulafulgin irrigation
topic Inflammation and Infection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596195/
https://www.ncbi.nlm.nih.gov/pubmed/33145176
http://dx.doi.org/10.1016/j.eucr.2020.101468
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