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Carbonic Anhydrase 12 Protects Endplate Cartilage From Degeneration Regulated by IGF-1/PI3K/CREB Signaling Pathway

Lumbar intervertebral disc degeneration (IVDD) is the most common cause of low back pain (LBP). Among all the factors leading to IVDD, lumbar cartilage endplate (LCE) degeneration is considered a key factor. In the present study, we investigate the effect and regulation of carbonic anhydrase 12 (CA1...

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Detalles Bibliográficos
Autores principales: Zhao, Xing, Shen, Panyang, Li, Haidong, Yang, Yute, Guo, Jiandong, Chen, Shuai, Ma, Yan, Sheng, Jiamin, Shen, Shuying, Liu, Gang, Fang, Xiangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596245/
https://www.ncbi.nlm.nih.gov/pubmed/33178705
http://dx.doi.org/10.3389/fcell.2020.595969