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Copy number variant analysis and expression profiling of the olfactory receptor-rich 11q11 region in obesity predisposition

Genome-wide copy number surveys associated chromosome 11q11 with obesity. As this is an olfactory receptor-rich region, we hypothesize that genetic variation in olfactory receptor genes might be implicated in the pathogenesis of obesity. Multiplex Amplicon Quantification analysis was applied to scre...

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Detalles Bibliográficos
Autores principales: Diels, Sara, Huybreghts, Sander, Van Hoorenbeeck, Kim, Massa, Guy, Verrijken, An, Verhulst, Stijn L., Van Gaal, Luc F., Van Hul, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596328/
https://www.ncbi.nlm.nih.gov/pubmed/33145169
http://dx.doi.org/10.1016/j.ymgmr.2020.100656