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Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts

Biocontainment systems are needed to neutralize genetically modified organisms (GMOs) that pose ecological threats outside of controlled environments. In contrast, benign selection markers complement GMOs with reduced fitness. Benign selection agents serve as alternatives to antibiotics, which are c...

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Detalles Bibliográficos
Autores principales: Yoo, Justin I., Seppälä, Susanna, OʼMalley, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596524/
https://www.ncbi.nlm.nih.gov/pubmed/33122649
http://dx.doi.org/10.1038/s41467-020-19271-1

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