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Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts
Biocontainment systems are needed to neutralize genetically modified organisms (GMOs) that pose ecological threats outside of controlled environments. In contrast, benign selection markers complement GMOs with reduced fitness. Benign selection agents serve as alternatives to antibiotics, which are c...
Autores principales: | Yoo, Justin I., Seppälä, Susanna, OʼMalley, Michelle A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596524/ https://www.ncbi.nlm.nih.gov/pubmed/33122649 http://dx.doi.org/10.1038/s41467-020-19271-1 |
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