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A wearable heart rate measurement device for children with autism spectrum disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by early impairment in social and communication domains and autonomic nervous system unbalance. This study evaluated heart rate (HR) as a possible indicator of stress response in children with ASD as compared to children...

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Autores principales: Fioriello, Francesca, Maugeri, Andrea, D’Alvia, Livio, Pittella, Erika, Piuzzi, Emanuele, Rizzuto, Emanuele, Del Prete, Zaccaria, Manti, Filippo, Sogos, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596550/
https://www.ncbi.nlm.nih.gov/pubmed/33122808
http://dx.doi.org/10.1038/s41598-020-75768-1
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author Fioriello, Francesca
Maugeri, Andrea
D’Alvia, Livio
Pittella, Erika
Piuzzi, Emanuele
Rizzuto, Emanuele
Del Prete, Zaccaria
Manti, Filippo
Sogos, Carla
author_facet Fioriello, Francesca
Maugeri, Andrea
D’Alvia, Livio
Pittella, Erika
Piuzzi, Emanuele
Rizzuto, Emanuele
Del Prete, Zaccaria
Manti, Filippo
Sogos, Carla
author_sort Fioriello, Francesca
collection PubMed
description Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by early impairment in social and communication domains and autonomic nervous system unbalance. This study evaluated heart rate (HR) as a possible indicator of stress response in children with ASD as compared to children with language disorder (LD). Twenty-four patients [mean age = 42.62 months; SD = 8.14 months,12 with ASD (10 M/2F) and 12 with LD (8 M/4F)] underwent clinical [Leiter International Performance Scale-Revised, Autism Diagnostic Observation Schedule, second edition (ADOS-2)] and physiological evaluation (HR monitoring) during five interactive activities, while wearing an HR measurement device. IQ (ASD:IQ = 103.33 ± 12.85 vs. LD:IQ = 111.00 ± 8.88, p = 0.103) and fluid reasoning on the Leiter-R Scale were within the normal range in all subjects. Increased HR during the third activity (ADOS-2 bubble play) significantly correlated with autistic symptoms (r = 0.415; p = 0.044), while correlations between ADOS-2 total score and HR during the first activity (ADOS-2 free play; r = 0.368; p = 0.077), second activity (Leiter-R figure ground subscale; r = 0.373, p = 0.073), and fifth activity (ADOS-2 anticipation of a routine with objects; r = 0.368; p = 0.076) did not quite reach statistical significance. Applying a linear regression model, we found that the ADOS-2 total score significantly influenced HR variations (p = 0.023). HR monitoring may provide a better understanding of the stress-provoking situations for children with ASD. Furthermore, it could help clinicians detect the impact of the stressful condition on the autistic core and adress treatment strategy.
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spelling pubmed-75965502020-10-30 A wearable heart rate measurement device for children with autism spectrum disorder Fioriello, Francesca Maugeri, Andrea D’Alvia, Livio Pittella, Erika Piuzzi, Emanuele Rizzuto, Emanuele Del Prete, Zaccaria Manti, Filippo Sogos, Carla Sci Rep Article Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by early impairment in social and communication domains and autonomic nervous system unbalance. This study evaluated heart rate (HR) as a possible indicator of stress response in children with ASD as compared to children with language disorder (LD). Twenty-four patients [mean age = 42.62 months; SD = 8.14 months,12 with ASD (10 M/2F) and 12 with LD (8 M/4F)] underwent clinical [Leiter International Performance Scale-Revised, Autism Diagnostic Observation Schedule, second edition (ADOS-2)] and physiological evaluation (HR monitoring) during five interactive activities, while wearing an HR measurement device. IQ (ASD:IQ = 103.33 ± 12.85 vs. LD:IQ = 111.00 ± 8.88, p = 0.103) and fluid reasoning on the Leiter-R Scale were within the normal range in all subjects. Increased HR during the third activity (ADOS-2 bubble play) significantly correlated with autistic symptoms (r = 0.415; p = 0.044), while correlations between ADOS-2 total score and HR during the first activity (ADOS-2 free play; r = 0.368; p = 0.077), second activity (Leiter-R figure ground subscale; r = 0.373, p = 0.073), and fifth activity (ADOS-2 anticipation of a routine with objects; r = 0.368; p = 0.076) did not quite reach statistical significance. Applying a linear regression model, we found that the ADOS-2 total score significantly influenced HR variations (p = 0.023). HR monitoring may provide a better understanding of the stress-provoking situations for children with ASD. Furthermore, it could help clinicians detect the impact of the stressful condition on the autistic core and adress treatment strategy. Nature Publishing Group UK 2020-10-29 /pmc/articles/PMC7596550/ /pubmed/33122808 http://dx.doi.org/10.1038/s41598-020-75768-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Fioriello, Francesca
Maugeri, Andrea
D’Alvia, Livio
Pittella, Erika
Piuzzi, Emanuele
Rizzuto, Emanuele
Del Prete, Zaccaria
Manti, Filippo
Sogos, Carla
A wearable heart rate measurement device for children with autism spectrum disorder
title A wearable heart rate measurement device for children with autism spectrum disorder
title_full A wearable heart rate measurement device for children with autism spectrum disorder
title_fullStr A wearable heart rate measurement device for children with autism spectrum disorder
title_full_unstemmed A wearable heart rate measurement device for children with autism spectrum disorder
title_short A wearable heart rate measurement device for children with autism spectrum disorder
title_sort wearable heart rate measurement device for children with autism spectrum disorder
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596550/
https://www.ncbi.nlm.nih.gov/pubmed/33122808
http://dx.doi.org/10.1038/s41598-020-75768-1
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