Prevalence of High Tumor Mutational Burden and Association With Survival in Patients With Less Common Solid Tumors

IMPORTANCE: Tumor mutational burden (TMB) is a potential biomarker associated with response to immune checkpoint inhibitor therapies. The prognostic value associated with TMB in the absence of immunotherapy is uncertain. OBJECTIVE: To assess the prevalence of high TMB (TMB-H) and its association wit...

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Detalles Bibliográficos
Autores principales: Shao, Changxia, Li, Gerald, Huang, Lingkang, Pruitt, Scott, Castellanos, Emily, Frampton, Garrett, Carson, Kenneth R., Snow, Tamara, Singal, Gaurav, Fabrizio, David, Alexander, Brian M., Jin, Fan, Zhou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596577/
https://www.ncbi.nlm.nih.gov/pubmed/33119110
http://dx.doi.org/10.1001/jamanetworkopen.2020.25109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596577/
https://www.ncbi.nlm.nih.gov/pubmed/33119110
http://dx.doi.org/10.1001/jamanetworkopen.2020.25109

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