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T-Cell Hyperactivation and Paralysis in Severe COVID-19 Infection Revealed by Single-Cell Analysis

Severe COVID-19 patients show various immunological abnormalities including T-cell reduction and cytokine release syndrome, which can be fatal and is a major concern of the pandemic. However, it is poorly understood how T-cell dysregulation can contribute to the pathogenesis of severe COVID-19. Here...

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Detalles Bibliográficos
Autores principales: Kalfaoglu, Bahire, Almeida-Santos, José, Tye, Chanidapa Adele, Satou, Yorifumi, Ono, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596772/
https://www.ncbi.nlm.nih.gov/pubmed/33178221
http://dx.doi.org/10.3389/fimmu.2020.589380