Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories

Stem and progenitor cell fate transitions constitute key decision points in organismal development that enable access to a developmental path or actively preclude others. Using the hematopoietic system, we analyzed the relative importance of cell fate–promoting mechanisms versus negating fate-suppre...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Kirby D., Conn, Daniel J., Shishkova, Evgenia, Katsumura, Koichi R., Liu, Peng, Shen, Siqi, Ranheim, Erik A., Kraus, Sean G., Wang, Weixin, Calvo, Katherine R., Hsu, Amy P., Holland, Steven M., Coon, Joshua J., Keles, Sunduz, Bresnick, Emery H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596813/
https://www.ncbi.nlm.nih.gov/pubmed/32736380
http://dx.doi.org/10.1084/jem.20191526

Ejemplares similares

Ejemplares similares